Standard

Nicotine metabolite ratio in current smokers

TSPYL5 · rs2045966

Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.

What each result means

C/C Published research associates this genotype with typical/baseline likelihood of Nicotine metabolite ratio in current smokers — no copies of the reported risk allele. (GWAS Catalog, Cancer Res 2016, PMID:27488534)

C/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Nicotine metabolite ratio in current smokers. (GWAS Catalog, Cancer Res 2016, PMID:27488534)

G/G Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Nicotine metabolite ratio in current smokers compared to the general population. (GWAS Catalog, Cancer Res 2016, PMID:27488534)

Source: GWAS Catalog, Cancer Res 2016, PMID:27488534

Questions about rs2045966

What is rs2045966?

rs2045966 is a single position in the genome, in or near the TSPYL5 gene. Published research associates it with nicotine metabolite ratio in current smokers. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs2045966 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2045966 come from?

GWAS Catalog, Cancer Res 2016, PMID:27488534. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

← See all variants