Standard
middle facial morphology traits (quantitative measurement)
DCHS2 · rs2045323
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
A/A
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of middle facial morphology traits (quantitative measurement) compared to the general population.
A/G
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with middle facial morphology traits (quantitative measurement).
G/G
Published research associates this genotype with typical/baseline likelihood of middle facial morphology traits (quantitative measurement) — no copies of the reported risk allele.
Source
A genome-wide association scan implicates DCHS2, RUNX2, GLI3, PAX1 and EDAR in human facial variation
Adhikari K,
Fuentes-Guajardo M,
Quinto-Sánchez M,
Mendoza-Revilla J,
Camilo Chacón-Duque J,
Acuña-Alonzo V,
Jaramillo C,
Arias W,
Lozano RB,
Pérez GM,
Gómez-Valdés J,
Villamil-Ramírez H
and 20 more — show all
Hunemeier T,
Ramallo V,
Silva de Cerqueira CC,
Hurtado M,
Villegas V,
Granja V,
Gallo C,
Poletti G,
Schuler-Faccini L,
Salzano FM,
Bortolini MC,
Canizales-Quinteros S,
Cheeseman M,
Rosique J,
Bedoya G,
Rothhammer F,
Headon D,
González-José R,
Balding D,
Ruiz-Linares A
Nature communications · 2016 · PMID 27193062 · open access
Questions about rs2045323
What is rs2045323?
rs2045323 is a single position in the genome, in or near the DCHS2 gene. Published research associates it with middle facial morphology traits (quantitative measurement). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs2045323 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs2045323 come from?
GWAS Catalog, Nat Commun 2016, PMID:27193062. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
← See all variants