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Leukocyte telomere length

UNC80 · rs2041524

Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.

What the study found

Who was studied 327,790 British ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.025 higher (95% confidence interval 0.021-0.029); p = 4 × 10⁻²⁵.

How common The G allele had a frequency of about 40% in the people studied.

Where it sits Chromosome 2, band 2q34 — in an intron of UNC80.

What each result means

C/C Published research associates this genotype with typical/baseline likelihood of Leukocyte telomere length — no copies of the reported risk allele.

C/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Leukocyte telomere length.

G/G Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Leukocyte telomere length compared to the general population.

Source

Whole exome sequencing analyses reveal novel genes in telomere length and their biomedical implications

Liu WS, Wu BS, Yang L, Chen SD, Zhang YR, Deng YT, Wu XR, He XY, Yang J, Feng JF, Cheng W, Xu YM

and 1 more — show all

Yu JT

GeroScience · 2024 · PMID 38837026

Questions about rs2041524

What is rs2041524?

rs2041524 is a single position in the genome, in or near the UNC80 gene. Published research associates it with leukocyte telomere length. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs2041524 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2041524 come from?

GWAS Catalog, GeroScience 2024, PMID:38837026. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Leukocyte telomere length (rs2041524). MyGeneLog™. https://www.mygenelog.com/variants/rs2041524

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