4 445224223222Reads by AI crawlersClaude5ChatGPT2Google · Gemini0Perplexity2Meta AI4Microsoft · Copilot2Amazon2Apple3China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others22Total44Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 882 Sardinian cases, 872 Sardinian controls; replicated in 1,775 Sardinian cases, 2,005 Sardinian controls.
The effect
Each copy of the G allele carried 2.05 times the odds of Multiple sclerosis; p = 1 × 10−20.
How common The G allele had a frequency of about 26% in the people studied.
Where it sits Chromosome 6, band 6p21.32 — inside HLA-DQA1.
What each result means
A/ANo copy of the version the research linked to Multiple sclerosis. This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Multiple sclerosis. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Multiple sclerosis. That is the strongest link of the three results. A link in a study is not a diagnosis.
rs2040406 is a single position in the genome, in or near the HLA-DQB1 gene. Published research associates it with multiple sclerosis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs2040406 linked to?
On MyGeneLog this position is linked to Multiple Sclerosis. The research behind each link, and its sources, are set out on that condition page.
Does having rs2040406 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs2040406 come from?
GWAS Catalog, Nat Genet 2010, PMID:20453840. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
4 445224223222Reads by AI crawlersClaude5ChatGPT2Google · Gemini0Perplexity2Meta AI4Microsoft · Copilot2Amazon2Apple3China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others22Total44Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.