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Body mass index

LINC01419 · rs2033732

Where this position leads

Conditions: Childhood Body Mass Index, Obesity and Body Weight

rs2033732 Condition: Childhood Body Mass Index Childhood Body Mass Index Condition Condition: Obesity and Body Weight Obesity and Body Weight Condition rs2033732 rs2033732 LINC01419

What the study found

Who was studied up to 72,390 Japanese ancestry women, up to 85,894 Japanese ancestry men; replicated in up to 10,048 Japanese ancestry women, up to 5,098 Japanese ancestry men, up to 181,999 European ancestry women, up to 140,155 European ancestry controls.

The effect Each copy of the C allele shifted the measure 0.016 higher (95% confidence interval 0.01-0.022); p = 9 × 10−9.

How common The C allele had a frequency of about 76% in the people studied.

Where it sits Chromosome 8, band 8q21.2 — between genes, 5 kb from TPM3P3.

What each result means

C/C Two copies of the version the research linked to Body mass index. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Body mass index. That is a smaller link than two copies.
T/T No copy of the version the research linked to Body mass index. This is the starting point the study compared everyone against.
Source

Questions about rs2033732

What is rs2033732?

rs2033732 is a single position in the genome, in or near the LINC01419 gene. Published research associates it with body mass index. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs2033732 linked to?

On MyGeneLog this position is linked to Childhood Body Mass Index, Obesity and Body Weight. The research behind each link, and its sources, are set out on that condition page.

Does having rs2033732 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2033732 come from?

GWAS Catalog, Nature genetics 2017, PMID:28892062. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Body mass index (rs2033732). MyGeneLog™. https://www.mygenelog.com/variants/rs2033732

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