Sensitive

Major depressive disorder (MTAG)

BSN · rs2029591

Where this position leads

Condition: Major Depressive Disorder

rs2029591 Condition: Major Depressive Disorder Major Depressive Disorder Condition rs2029591 rs2029591 BSN

What the study found

Who was studied at least 170,756 European ancestry cases, at least 329,443 European ancestry controls.

The effect Each copy of the T allele shifted the measure 0.0338 higher (95% confidence interval 0.023-0.045); p = 1 × 10−9.

How common The T allele had a frequency of about 16% in the people studied.

Where it sits Chromosome 3, band 3p21.31 — in an intron of BSN.

What each result means

C/C No copy of the version the research linked to Major depressive disorder (MTAG). This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Major depressive disorder (MTAG). That is a smaller link than two copies.
T/T Two copies of the version the research linked to Major depressive disorder (MTAG). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs2029591

What is rs2029591?

rs2029591 is a single position in the genome, in or near the BSN gene. Published research associates it with major depressive disorder (mtag). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs2029591 linked to?

On MyGeneLog this position is linked to Major Depressive Disorder. The research behind each link, and its sources, are set out on that condition page.

Does having rs2029591 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2029591 come from?

GWAS Catalog, Translational psychiatry 2021, PMID:33479212. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Major depressive disorder (MTAG) (rs2029591). MyGeneLog™. https://www.mygenelog.com/variants/rs2029591

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