Sensitive

Broad depression or schizophrenia

SPATA31D1 · rs2026194

Where this position leads

Condition: Schizophrenia

rs2026194 Condition: Schizophrenia Schizophrenia Condition rs2026194 rs2026194 SPATA31D1

What the study found

Who was studied 9,240 European ancestry broad depression cases, 9,519 European ancestry broad depression controls, 51,258 European ancestry individuals, 36,989 European and East Asian ancestry schizophrenia cases, 113,075 European and East Asian ancestry schizophrenia controls; replicated in 322,580 individuals.

The effect The reported allele is T; the catalogue records no effect size ; p = 2 × 10−9.

How common The T allele had a frequency of about 24% in the people studied.

Where it sits Chromosome 9, band 9q21.32 — between genes, 40 kb from MTCO3P40.

What each result means

C/C No copy of the version the research linked to Broad depression or schizophrenia. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Broad depression or schizophrenia. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Broad depression or schizophrenia. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs2026194

What is rs2026194?

rs2026194 is a single position in the genome, in or near the SPATA31D1 gene. Published research associates it with broad depression or schizophrenia. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs2026194 linked to?

On MyGeneLog this position is linked to Schizophrenia. The research behind each link, and its sources, are set out on that condition page.

Does having rs2026194 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2026194 come from?

GWAS Catalog, Mol Psychiatry 2019, PMID:30626913. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Broad depression or schizophrenia (rs2026194). MyGeneLog™. https://www.mygenelog.com/variants/rs2026194

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