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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 339 European ancestry male cases, 639 European ancestry male controls; replicated in 380 European ancestry male cases, 1,228 European ancestry male controls.
The effect
Each copy of the A allele carried 1.71 times the odds of Primary aldosteronism (95% confidence interval 1.49-1.96); p = 2 × 10−14.
Where it sits Chromosome 13, band 13q13.1 — between genes, 87.3 kb from RXFP2.
What each result means
A/ATwo copies of the version the research linked to Primary aldosteronism. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Primary aldosteronism. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Primary aldosteronism. This is the starting point the study compared everyone against.
Nature communications · 2022 · PMID 36057693 · open access
Questions about rs2025908
What is rs2025908?
rs2025908 is a single position in the genome, in or near the near RXFP2 gene. Published research associates it with primary aldosteronism. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs2025908 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs2025908 come from?
GWAS Catalog, Nature communications 2022, PMID:36057693. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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