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Inguinal hernia

EIF3M · rs201861

Where this position leads

Condition: Inguinal Hernia

rs201861 Condition: Inguinal Hernia Inguinal Hernia Condition rs201861 rs201861 EIF3M

What the study found

Who was studied 13,047 European ancestry cases, 262,499 European ancestry controls; replicated in 4,450 European ancestry cases, 87,398 European ancestry controls.

The effect The reported allele is C; the catalogue records no effect size ; p = 3 × 10−15.

How common The C allele had a frequency of about 76% in the people studied.

Where it sits Chromosome 11, band 11p13 — in an intron of EIF3M.

What each result means

C/C Two copies of the version the research linked to Inguinal hernia. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Inguinal hernia. That is a smaller link than two copies.
T/T No copy of the version the research linked to Inguinal hernia. This is the starting point the study compared everyone against.
Source

Questions about rs201861

What is rs201861?

rs201861 is a single position in the genome, in or near the EIF3M gene. Published research associates it with inguinal hernia. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs201861 linked to?

On MyGeneLog this position is linked to Inguinal Hernia. The research behind each link, and its sources, are set out on that condition page.

Does having rs201861 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs201861 come from?

GWAS Catalog, Hernia : the journal of hernias and abdominal wall surgery 2022, PMID:34382107. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Inguinal hernia (rs201861). MyGeneLog™. https://www.mygenelog.com/variants/rs201861

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