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Vertex-wise sulcal depth

ATOX1 · rs2016409

What the study found

Who was studied 33,748 European ancestry individuals.

The effect Each copy of the G allele shifted the measure 8.24 z score higher; p = 2 × 10−16.

How common The G allele had a frequency of about 26% in the people studied.

Where it sits Chromosome 5, band 5q33.1 — in an intron of ATOX1.

What each result means

G/G Two copies of the version the research linked to Vertex-wise sulcal depth. That is the strongest link of the three results. A link in a study is not a diagnosis.
G/T One copy of the version the research linked to Vertex-wise sulcal depth. That is a smaller link than two copies.
T/T No copy of the version the research linked to Vertex-wise sulcal depth. This is the starting point the study compared everyone against.
Source

Questions about rs2016409

What is rs2016409?

rs2016409 is a single position in the genome, in or near the ATOX1 gene. Published research associates it with vertex-wise sulcal depth. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs2016409 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2016409 come from?

GWAS Catalog, Science advances 2021, PMID:34910505. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Vertex-wise sulcal depth (rs2016409). MyGeneLog™. https://www.mygenelog.com/variants/rs2016409

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