Sensitive

Colorectal cancer

EFCAB2 · rs201395236

Where this position leads

Condition: Colorectal Cancer

rs201395236 Condition: Colorectal Cancer Colorectal Cancer Condition rs201395236 rs201395236 EFCAB2

What the study found

Who was studied 22,775 East Asian ancestry cases, 47,731 East Asian ancestry controls.

The effect Each copy of the T allele carried 1.75 times the odds of Colorectal cancer (95% confidence interval 1.43-2.13); p = 5 × 10−8.

How common The T allele had a frequency of about 99% in the people studied.

Where it sits Chromosome 1, band 1q44 — in an intron of EFCAB2.

What each result means

C/C No copy of the version the research linked to Colorectal cancer. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Colorectal cancer. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Colorectal cancer. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs201395236

What is rs201395236?

rs201395236 is a single position in the genome, in or near the EFCAB2 gene. Published research associates it with colorectal cancer. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs201395236 linked to?

On MyGeneLog this position is linked to Colorectal Cancer. The research behind each link, and its sources, are set out on that condition page.

Does having rs201395236 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs201395236 come from?

GWAS Catalog, Gastroenterology 2018, PMID:30529582. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Colorectal cancer (rs201395236). MyGeneLog™. https://www.mygenelog.com/variants/rs201395236

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