Standard

Central retinal vein equivalent

TSPAN10 · rs201259422

What the study found

Who was studied 14,740 European ancestry individuals, 5,113 Asian ancestry individuals, 3,345 African American individuals, 1,077 Hispanic individuals; replicated in 5,472 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.06 lower (95% confidence interval 0.04-0.08); p = 4 × 10−9.

Where it sits Chromosome 17, band 17q25.3 — a missense change in TSPAN10.

What each result means

A/A Two copies of the version the research linked to Central retinal vein equivalent. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Central retinal vein equivalent. That is a smaller link than two copies.
G/G No copy of the version the research linked to Central retinal vein equivalent. This is the starting point the study compared everyone against.
Source

Questions about rs201259422

What is rs201259422?

rs201259422 is a single position in the genome, in or near the TSPAN10 gene. Published research associates it with central retinal vein equivalent. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs201259422 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs201259422 come from?

GWAS Catalog, Circulation. Cardiovascular genetics 2016, PMID:26567291. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Central retinal vein equivalent (rs201259422). MyGeneLog™. https://www.mygenelog.com/variants/rs201259422

← See all variants