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Who was studied 5,571 Chinese ancestry individuals; replicated in 2,981 Chinese ancestry individuals.
The effect
Each copy of the G allele shifted the measure 6.18 z score lower; p = 7 × 10−10.
Where it sits Chromosome 2, band 2p25.3 — inside COLEC11.
What each result means
C/CNo copy of the version the research linked to Intraocular pressure. This is the starting point the study compared everyone against.
C/GOne copy of the version the research linked to Intraocular pressure. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Intraocular pressure. That is the strongest link of the three results. A link in a study is not a diagnosis.
Science China. Life sciences · 2019 · PMID 30591961
Questions about rs201143466
What is rs201143466?
rs201143466 is a single position in the genome, in or near the COLEC11 gene. Published research associates it with intraocular pressure. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs201143466 linked to?
On MyGeneLog this position is linked to Intraocular Pressure. The research behind each link, and its sources, are set out on that condition page.
Does having rs201143466 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs201143466 come from?
GWAS Catalog, Science China. Life sciences 2019, PMID:30591961. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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