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Hyperuricemia in low fiber intake

near PRPF3 · rs200441991

What the study found

Who was studied 47,911 Korean ancestry individuals.

The effect Each copy of the G allele carried 1.22 times the odds of Hyperuricemia in low fiber intake (95% confidence interval 1.14-1.31); p = 8 × 10−9.

Where it sits Chromosome 1, band 1q21.2 — between genes, 4.3 kb from PRPF3.

What each result means

G/G Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Hyperuricemia in low fiber intake compared to the general population.
G/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Hyperuricemia in low fiber intake.
T/T Published research associates this genotype with typical/baseline likelihood of Hyperuricemia in low fiber intake — no copies of the reported risk allele.
Source

Questions about rs200441991

What is rs200441991?

rs200441991 is a single position in the genome, in or near the near PRPF3 gene. Published research associates it with hyperuricemia in low fiber intake. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs200441991 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs200441991 come from?

GWAS Catalog, Scientific reports 2025, PMID:40835619. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Hyperuricemia in low fiber intake (rs200441991). MyGeneLog™. https://www.mygenelog.com/variants/rs200441991

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