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Total cholesterol levels

PMFBP1 · rs200435297

What the study found

Who was studied 58,701 Korean ancestry individuals.

The effect Each copy of the C allele shifted the measure 2.28 lower (95% confidence interval 1.66-2.9); p = 7 × 10−13.

Where it sits Chromosome 16, band 16q22.2 — in an intron of PMFBP1.

What each result means

C/C Two copies of the version the research linked to Total cholesterol levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Total cholesterol levels. That is a smaller link than two copies.
T/T No copy of the version the research linked to Total cholesterol levels. This is the starting point the study compared everyone against.
Source

Questions about rs200435297

What is rs200435297?

rs200435297 is a single position in the genome, in or near the PMFBP1 gene. Published research associates it with total cholesterol levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs200435297 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs200435297 come from?

GWAS Catalog, Biomedicines 2022, PMID:35884923. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Total cholesterol levels (rs200435297). MyGeneLog™. https://www.mygenelog.com/variants/rs200435297

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