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Gamma glutamyl transferase levels

SIGLEC1 · rs200137244

What the study found

Who was studied 288,127 East Asian ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.139 higher (95% confidence interval 0.1-0.178); p = 3 × 10−12.

How common The G allele had a frequency of about 1% in the people studied.

Where it sits Chromosome 20, band 20p13 — a missense change in SIGLEC1.

What each result means

A/A No copy of the version the research linked to Gamma glutamyl transferase levels. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Gamma glutamyl transferase levels. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Gamma glutamyl transferase levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs200137244

What is rs200137244?

rs200137244 is a single position in the genome, in or near the SIGLEC1 gene. Published research associates it with gamma glutamyl transferase levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs200137244 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs200137244 come from?

GWAS Catalog, Nature communications 2022, PMID:36333282. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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Gamma glutamyl transferase levels (rs200137244). MyGeneLog™. https://www.mygenelog.com/variants/rs200137244

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