Sensitive

Antipsychotic drug-induced QTc interval change in schizophrenia

ATAD3B · rs200050752

Where this position leads

Condition: Schizophrenia

rs200050752 Condition: Schizophrenia Schizophrenia Condition rs200050752 rs200050752 ATAD3B

What the study found

Who was studied 2,040 Chinese Han ancestry individuals.

The effect Each copy of the T allele shifted the measure 36 higher (95% confidence interval 25.17-46.87); p = 4 × 10−8.

How common The T allele had a frequency of about 1% in the people studied.

Where it sits Chromosome 1, band 1p36.33 — a missense change in ATAD3B.

What each result means

C/C No copy of the version the research linked to Antipsychotic drug-induced QTc interval change in schizophrenia. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Antipsychotic drug-induced QTc interval change in schizophrenia. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Antipsychotic drug-induced QTc interval change in schizophrenia. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs200050752

What is rs200050752?

rs200050752 is a single position in the genome, in or near the ATAD3B gene. Published research associates it with antipsychotic drug-induced qtc interval change in schizophrenia. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs200050752 linked to?

On MyGeneLog this position is linked to Schizophrenia. The research behind each link, and its sources, are set out on that condition page.

Does having rs200050752 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs200050752 come from?

GWAS Catalog, Translational psychiatry 2022, PMID:35136033. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Antipsychotic drug-induced QTc interval change in schizophrenia (rs200050752). MyGeneLog™. https://www.mygenelog.com/variants/rs200050752

← See all variants