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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 2,524 European ancestry individuals.
The effect
Each copy of the G allele shifted the measure 0.157 lower (95% confidence interval 0.11-0.2); p = 7 × 10−11.
How common The G allele had a frequency of about 15% in the people studied.
Where it sits Chromosome 22, band 22q11.23 — in an intron of MIF-AS1.
What each result means
G/GTwo copies of the version the research linked to Cerebrospinal fluid protein MIF levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
G/TOne copy of the version the research linked to Cerebrospinal fluid protein MIF levels. That is a smaller link than two copies.
T/TNo copy of the version the research linked to Cerebrospinal fluid protein MIF levels. This is the starting point the study compared everyone against.
Science translational medicine · 2026 · PMID 42054495
Questions about rs2000466
What is rs2000466?
rs2000466 is a single position in the genome, in or near the MIF-AS1 gene. Published research associates it with cerebrospinal fluid protein mif levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs2000466 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs2000466 come from?
GWAS Catalog, Science translational medicine 2026, PMID:42054495. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
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Cerebrospinal fluid protein MIF levels (rs2000466). MyGeneLog™. https://www.mygenelog.com/variants/rs2000466