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ghrelin levels in overweight individuals

near SERPINB9 · rs199890456

What the study found

Who was studied 2,220 Sub-Saharan African ancestry individuals; replicated in 1,261 African American individuals.

The effect Each copy of the T allele shifted the measure 0.301 lower (95% confidence interval 0.21-0.39); p = 9 × 10−12.

Where it sits Chromosome 6, band 6p25.2 — between genes, 11.4 kb from SERPINB9.

What each result means

C/C No copy of the version the research linked to ghrelin levels in overweight individuals. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to ghrelin levels in overweight individuals. That is a smaller link than two copies.
T/T Two copies of the version the research linked to ghrelin levels in overweight individuals. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs199890456

What is rs199890456?

rs199890456 is a single position in the genome, in or near the near SERPINB9 gene. Published research associates it with ghrelin levels in overweight individuals. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs199890456 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs199890456 come from?

GWAS Catalog, Genome medicine 2021, PMID:34620218. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

ghrelin levels in overweight individuals (rs199890456). MyGeneLog™. https://www.mygenelog.com/variants/rs199890456

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