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Who was studied 165,056 East Asian ancestry individuals.
The effect
Each copy of the A allele shifted the measure 0.104 lower (95% confidence interval 0.086-0.123); p = 8 × 10−29.
How common The A allele had a frequency of about 1% in the people studied.
Where it sits Chromosome 12, band 12q13.13 — a missense change in SP7.
What ClinVar records
ClassificationLikely benign; criteria provided, single submitter (1 of 4 stars, 1 submitter), last evaluated 2025-07-29.
ClinVar record 744269NM_001173467.3(SP7):c.865C>T (p.Arg289Trp)
What this is ClinVar's aggregate record for this position (as of its 2026-10-19 release), not a result about you. A classification describes the variant against the condition named, as laboratories submitted it. Whether a person carries this variant, and what that would mean for them, is a question for a clinical test and a genetic counsellor.
What each result means
A/ATwo copies of the version the research linked to Height. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Height. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Height. This is the starting point the study compared everyone against.
rs199673881 is a single position in the genome, in or near the SP7 gene. Published research associates it with height. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs199673881 linked to?
On MyGeneLog this position is linked to Height. The research behind each link, and its sources, are set out on that condition page.
Does having rs199673881 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs199673881 come from?
GWAS Catalog, Nature genetics 2021, PMID:34594039. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 12237Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple3China (ByteDance, Huawei, Baidu…)0Others7Total12Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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