Standard

Hirsutism

FGF5 · rs199649605

Where this position leads

Condition: Hirsutism

rs199649605 Condition: Hirsutism Hirsutism Condition rs199649605 rs199649605 FGF5

What the study found

Who was studied 502 Finnish ancestry female cases, 219,249 Finnish ancestry female controls.

The effect Each copy of the T allele carried 5.02 times the odds of Hirsutism (95% confidence interval 3.06-8.21); p = 1 × 10−10.

How common The T allele had a frequency of about 0% in the people studied.

Where it sits Chromosome 4, band 4q21.21 — a missense change in FGF5.

What each result means

C/C Published research associates this genotype with typical/baseline likelihood of Hirsutism — no copies of the reported risk allele.
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Hirsutism.
T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Hirsutism compared to the general population.
Source

Questions about rs199649605

What is rs199649605?

rs199649605 is a single position in the genome, in or near the FGF5 gene. Published research associates it with hirsutism. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs199649605 linked to?

On MyGeneLog this position is linked to Hirsutism. The research behind each link, and its sources, are set out on that condition page.

Does having rs199649605 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs199649605 come from?

GWAS Catalog, The Journal of investigative dermatology 2026, PMID:42190866. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Hirsutism (rs199649605). MyGeneLog™. https://www.mygenelog.com/variants/rs199649605

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