Sensitive

Metabolic syndrome

near LPL · rs1992442

Where this position leads

Condition: Metabolic Syndrome

rs1992442 Condition: Metabolic Syndrome Metabolic Syndrome Condition rs1992442 rs1992442 near LPL

What the study found

Who was studied 24,171 Taiwanese ancestry cases, 83,059 Taiwanese ancestry controls.

The effect Each copy of the A allele shifted the measure 0.16 lower (95% confidence interval 0.13-0.19); p = 2 × 10−32.

How common The A allele had a frequency of about 18% in the people studied.

Where it sits Chromosome 8, band 8p21.3 — between genes, 28.6 kb from LPL.

What each result means

A/A Two copies of the version the research linked to Metabolic syndrome. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/C One copy of the version the research linked to Metabolic syndrome. That is a smaller link than two copies.
C/C No copy of the version the research linked to Metabolic syndrome. This is the starting point the study compared everyone against.
Source

Questions about rs1992442

What is rs1992442?

rs1992442 is a single position in the genome, in or near the near LPL gene. Published research associates it with metabolic syndrome. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs1992442 linked to?

On MyGeneLog this position is linked to Metabolic Syndrome. The research behind each link, and its sources, are set out on that condition page.

Does having rs1992442 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs1992442 come from?

GWAS Catalog, Nutrients 2023, PMID:38201907. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Metabolic syndrome (rs1992442). MyGeneLog™. https://www.mygenelog.com/variants/rs1992442

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