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Liver enzyme levels (gamma-glutamyl transferase)

ASAP3 · rs1986133

What the study found

Who was studied 437,194 European ancestry individuals; replicated in 315,572 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.00592 lower (95% confidence interval 0.0048-0.007); p = 1 × 10−27.

How common The C allele had a frequency of about 31% in the people studied.

Where it sits Chromosome 1, band 1p36.12 — in an intron of ASAP3.

What each result means

C/C Two copies of the version the research linked to Liver enzyme levels (gamma-glutamyl transferase). That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Liver enzyme levels (gamma-glutamyl transferase). That is a smaller link than two copies.
T/T No copy of the version the research linked to Liver enzyme levels (gamma-glutamyl transferase). This is the starting point the study compared everyone against.
Source

Questions about rs1986133

What is rs1986133?

rs1986133 is a single position in the genome, in or near the ASAP3 gene. Published research associates it with liver enzyme levels (gamma-glutamyl transferase). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs1986133 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs1986133 come from?

GWAS Catalog, Nature communications 2021, PMID:33972514. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Liver enzyme levels (gamma-glutamyl transferase) (rs1986133). MyGeneLog™. https://www.mygenelog.com/variants/rs1986133

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