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Who was studied 6,056 European ancestry cases, 907,977 European ancestry controls, 4,661 East Asian ancestry cases, 354,129 East Asian ancestry controls, 5,450 African, Admixed American, European, East Asian, South Asian or unknown ancestry cases, 1,168,268 African, Admixed American, European, East Asian, South Asian or unknown ancestry controls.
The effect
Each copy of the A allele shifted the measure 0.083 lower (95% confidence interval 0.057-0.109); p = 5 × 10−10.
Where it sits Chromosome 8, band 8q24.13 — between genes, 39.8 kb from LINC02964.
What each result means
A/ATwo copies of the version the research linked to Thyroid cancer. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Thyroid cancer. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Thyroid cancer. This is the starting point the study compared everyone against.
Nature communications · 2026 · PMID 42431967 · open access
Questions about rs1979221
What is rs1979221?
rs1979221 is a single position in the genome, in or near the near LINC02964 gene. Published research associates it with thyroid cancer. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs1979221 linked to?
On MyGeneLog this position is linked to Thyroid Cancer. The research behind each link, and its sources, are set out on that condition page.
Does having rs1979221 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs1979221 come from?
GWAS Catalog, Nature communications 2026, PMID:42431967. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Thyroid cancer (rs1979221). MyGeneLog™. https://www.mygenelog.com/variants/rs1979221