Standard

Body shape phenotype PC2

near POLR3KP2 · rs1979110

Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.

What the study found

Who was studied 460,198 European ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.016 lower (95% confidence interval 0.011-0.021); p = 2 × 10⁻¹⁰.

How common The G allele had a frequency of about 74% in the people studied.

Where it sits Chromosome 17, band 17q25.1 — between genes, 13.5 kb from POLR3KP2.

What each result means

C/C No copy of the version the research linked to Body shape phenotype PC2. This is the starting point the study compared everyone against.

C/G One copy of the version the research linked to Body shape phenotype PC2. That is a smaller link than two copies.

G/G Two copies of the version the research linked to Body shape phenotype PC2. That is the strongest link of the three results. A link in a study is not a diagnosis.

Source

Tissue-specific genetic variation suggests distinct molecular pathways between body shape phenotypes and colorectal cancer

Peruchet-Noray L, Sedlmeier AM, Dimou N, Baurecht H, Fervers B, Fontvieille E, Konzok J, Tsilidis KK, Christakoudi S, Jansana A, Cordova R, Bohmann P

and 18 more — show all

Stein MJ, Weber A, Bézieau S, Brenner H, Chan AT, Cheng I, Figueiredo JC, Garcia-Etxebarria K, Moreno V, Newton CC, Schmit SL, Song M, Ulrich CM, Ferrari P, Viallon V, Carreras-Torres R, Gunter MJ, Freisling H

Science advances · 2024 · PMID 38640244 · open access

Questions about rs1979110

What is rs1979110?

rs1979110 is a single position in the genome, in or near the near POLR3KP2 gene. Published research associates it with body shape phenotype pc2. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs1979110 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs1979110 come from?

GWAS Catalog, Science advances 2024, PMID:38640244. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Body shape phenotype PC2 (rs1979110). MyGeneLog™. https://www.mygenelog.com/variants/rs1979110

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