Standard

Medication use (antihistamines for systemic use)

RBMS3 · rs1968514

Where this position leads

Condition: Medication Use as a Genetic Trait

rs1968514 Condition: Medication Use as a Genetic Trait Medication Use as a Genetic Trait Condition rs1968514 rs1968514 RBMS3

What the study found

Who was studied 13,984 European ancestry cases, 137,652 European ancestry controls.

The effect Each copy of the A allele shifted the measure 0.165 lower (95% confidence interval 0.11-0.22); p = 8 × 10−10.

How common The A allele had a frequency of about 6% in the people studied.

Where it sits Chromosome 3, band 3p24.1 — in an intron of RBMS3-AS2.

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Medication use (antihistamines for systemic use) compared to the general population.
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Medication use (antihistamines for systemic use).
G/G Published research associates this genotype with typical/baseline likelihood of Medication use (antihistamines for systemic use) — no copies of the reported risk allele.
Source

Questions about rs1968514

What is rs1968514?

rs1968514 is a single position in the genome, in or near the RBMS3 gene. Published research associates it with medication use (antihistamines for systemic use). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs1968514 linked to?

On MyGeneLog this position is linked to Medication Use as a Genetic Trait. The research behind each link, and its sources, are set out on that condition page.

Does having rs1968514 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs1968514 come from?

GWAS Catalog, Nat Commun 2019, PMID:31015401. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Medication use (antihistamines for systemic use) (rs1968514). MyGeneLog™. https://www.mygenelog.com/variants/rs1968514

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