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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 14,819 European ancestry cases, 941,863 European ancestry controls.
The effect
The reported allele is G; the catalogue records no effect size
; p = 2 × 10−8.
Where it sits Chromosome 5, band 5q35.1 — in a non-coding transcript of RPL7AP33.
What each result means
C/CNo copy of the version the research linked to Calcific aortic valve stenosis. This is the starting point the study compared everyone against.
C/GOne copy of the version the research linked to Calcific aortic valve stenosis. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Calcific aortic valve stenosis. That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature communications · 2024 · PMID 38494474 · open access
Questions about rs1965668
What is rs1965668?
rs1965668 is a single position in the genome, in or near the RPL7AP33 gene. Published research associates it with calcific aortic valve stenosis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs1965668 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs1965668 come from?
GWAS Catalog, Nature communications 2024, PMID:38494474. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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