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Who was studied 14,825 European ancestry cases, 2,680 cases, 380,970 European ancestry controls, 73,242 controls.
The effect
Each copy of the A allele carried 1.07 times the odds of Myocardial infarction (95% confidence interval 1.05-1.10); p = 3 × 10−8.
How common The A allele had a frequency of about 25% in the people studied.
Where it sits Chromosome 11, band 11p15.5 — between genes, 5.9 kb from FAM99A.
What each result means
A/ATwo copies of the version the research linked to Myocardial infarction. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Myocardial infarction. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Myocardial infarction. This is the starting point the study compared everyone against.
rs1964600 is a single position in the genome, in or near the MOB2 gene. Published research associates it with myocardial infarction. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs1964600 linked to?
On MyGeneLog this position is linked to Myocardial Infarction. The research behind each link, and its sources, are set out on that condition page.
Does having rs1964600 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs1964600 come from?
GWAS Catalog, European heart journal 2021, PMID:33532862. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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