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Histidine levels

NDRG2 · rs1958393

What the study found

Who was studied 114,897 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.0631 lower (95% confidence interval 0.05-0.076); p = 4 × 10−21.

How common The C allele had a frequency of about 89% in the people studied.

Where it sits Chromosome 14, band 14q11.2 — inside NDRG2.

What each result means

C/C Two copies of the version the research linked to Histidine levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/G One copy of the version the research linked to Histidine levels. That is a smaller link than two copies.
G/G No copy of the version the research linked to Histidine levels. This is the starting point the study compared everyone against.
Source

Questions about rs1958393

What is rs1958393?

rs1958393 is a single position in the genome, in or near the NDRG2 gene. Published research associates it with histidine levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs1958393 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs1958393 come from?

GWAS Catalog, PLoS biology 2022, PMID:35213538. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Histidine levels (rs1958393). MyGeneLog™. https://www.mygenelog.com/variants/rs1958393

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