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25-hydroxyvitamin D levels (skin colour stratified)

LINC02327 · rs1957114

What the study found

Who was studied 409,654 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.013 higher (95% confidence interval 0.0089-0.0171); p = 8 × 10−10.

How common The C allele had a frequency of about 37% in the people studied.

Where it sits Chromosome 14, band 14q12 — in an intron of LINC02327.

What each result means

C/C Two copies of the version the research linked to 25-hydroxyvitamin D levels (skin colour stratified). That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to 25-hydroxyvitamin D levels (skin colour stratified). That is a smaller link than two copies.
T/T No copy of the version the research linked to 25-hydroxyvitamin D levels (skin colour stratified). This is the starting point the study compared everyone against.
Source

Questions about rs1957114

What is rs1957114?

rs1957114 is a single position in the genome, in or near the LINC02327 gene. Published research associates it with 25-hydroxyvitamin d levels (skin colour stratified). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs1957114 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs1957114 come from?

GWAS Catalog, PLoS genetics 2023, PMID:37963177. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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25-hydroxyvitamin D levels (skin colour stratified) (rs1957114). MyGeneLog™. https://www.mygenelog.com/variants/rs1957114

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