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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 446,237 European ancestry individuals; replicated in 7,612 African ancestry individuals, 10,095 South Asian ancestry individuals.
The effect
Each copy of the C allele shifted the measure 0.019 lower (95% confidence interval 0.013-0.024); p = 1 × 10−11.
How common The C allele had a frequency of about 95% in the people studied.
Where it sits Chromosome 14, band 14q12 — in an intron of LINC02327.
What each result means
C/CTwo copies of the version the research linked to Urinary sodium excretion. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/TOne copy of the version the research linked to Urinary sodium excretion. That is a smaller link than two copies.
T/TNo copy of the version the research linked to Urinary sodium excretion. This is the starting point the study compared everyone against.
Nature communications · 2019 · PMID 31409800 · open access
Questions about rs1957111
What is rs1957111?
rs1957111 is a single position in the genome, in or near the PRKD1 gene. Published research associates it with urinary sodium excretion. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs1957111 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs1957111 come from?
GWAS Catalog, Nature communications 2019, PMID:31409800. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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