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Who was studied 15,771 East Asian ancestry cases, 178,777 East Asian ancestry controls, 170,756 European ancestry cases, 329,443 European ancestry controls.
The effect
Each copy of the A allele shifted the measure 0.00947 higher (95% confidence interval 0.0066-0.0123); p = 8 × 10−11.
How common The A allele had a frequency of about 62% in the people studied.
Where it sits Chromosome 14, band 14q21.1 — in an intron of LRFN5.
What each result means
A/ATwo copies of the version the research linked to Depression. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Depression. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Depression. This is the starting point the study compared everyone against.
JAMA psychiatry · 2021 · PMID 34586374 · open access
Questions about rs1950829
What is rs1950829?
rs1950829 is a single position in the genome, in or near the LRFN5 gene. Published research associates it with depression. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs1950829 linked to?
On MyGeneLog this position is linked to Endometriosis and Depression: Shared Genetics. The research behind each link, and its sources, are set out on that condition page.
Does having rs1950829 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs1950829 come from?
GWAS Catalog, JAMA psychiatry 2021, PMID:34586374. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 11227Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others7Total11Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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