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Leucine-rich repeat transmembrane protein FLRT2 levels

MACROD2 · rs1932953

What the study found

Who was studied 2,893 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.215 higher (95% confidence interval 0.15-0.28); p = 3 × 10−11.

How common The T allele had a frequency of about 21% in the people studied.

Where it sits Chromosome 20, band 20p12.1 — in an intron of MACROD2.

What each result means

G/G No copy of the version the research linked to Leucine-rich repeat transmembrane protein FLRT2 levels. This is the starting point the study compared everyone against.
G/T One copy of the version the research linked to Leucine-rich repeat transmembrane protein FLRT2 levels. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Leucine-rich repeat transmembrane protein FLRT2 levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs1932953

What is rs1932953?

rs1932953 is a single position in the genome, in or near the MACROD2 gene. Published research associates it with leucine-rich repeat transmembrane protein flrt2 levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs1932953 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs1932953 come from?

GWAS Catalog, Nature communications 2021, PMID:34857772. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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Leucine-rich repeat transmembrane protein FLRT2 levels (rs1932953). MyGeneLog™. https://www.mygenelog.com/variants/rs1932953

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