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Glycated hemoglobin in pregnancy

near TREX2 · rs192820967

What the study found

Who was studied 66,799 Chinese ancestry individuals; replicated in 45,280 Chinese ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.407 lower (95% confidence interval 0.31-0.5); p = 9 × 10−17.

How common The A allele had a frequency of about 2% in the people studied.

What each result means

A/A Two copies of the version the research linked to Glycated hemoglobin in pregnancy. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Glycated hemoglobin in pregnancy. That is a smaller link than two copies.
G/G No copy of the version the research linked to Glycated hemoglobin in pregnancy. This is the starting point the study compared everyone against.
Source

Questions about rs192820967

What is rs192820967?

rs192820967 is a single position in the genome, in or near the near TREX2 gene. Published research associates it with glycated hemoglobin in pregnancy. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs192820967 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs192820967 come from?

GWAS Catalog, Nature genetics 2026, PMID:42509370. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Glycated hemoglobin in pregnancy (rs192820967). MyGeneLog™. https://www.mygenelog.com/variants/rs192820967

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