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Insomnia

near TLR4 · rs1927902

Where this position leads

Condition: Insomnia

rs1927902 Condition: Insomnia Insomnia Condition rs1927902 rs1927902 near TLR4

What the study found

Who was studied 651,923 European ancestry males, 679,087 European ancestry females.

The effect Each copy of the T allele carried 1.05 times the odds of Insomnia (95% confidence interval 1.04-1.07); p = 1 × 10−14.

How common The T allele had a frequency of about 25% in the people studied.

Where it sits Chromosome 9, band 9q33.1 — between genes, 32 kb from TLR4.

What each result means

C/C No copy of the version the research linked to Insomnia. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Insomnia. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Insomnia. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs1927902

What is rs1927902?

rs1927902 is a single position in the genome, in or near the near TLR4 gene. Published research associates it with insomnia. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs1927902 linked to?

On MyGeneLog this position is linked to Insomnia. The research behind each link, and its sources, are set out on that condition page.

Does having rs1927902 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs1927902 come from?

GWAS Catalog, Nature genetics 2019, PMID:30804565. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Insomnia (rs1927902). MyGeneLog™. https://www.mygenelog.com/variants/rs1927902

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