Alzheimer's disease (onset between ages 58 and 79)
TRAPPC6A · rs192775394
0 312Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon0Apple0China (ByteDance, Huawei, Baidu…)0Others2Total3Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 7,316 European ancestry cases, 7,579 European ancestry controls.
The effect
Each copy of the C allele carried 1.88 times the odds of Alzheimer's disease (onset between ages 58 and 79) (95% confidence interval 1.52-2.33); p = 8 × 10−9.
How common The C allele had a frequency of about 2% in the people studied.
Where it sits Chromosome 19, band 19q13.32 — in an intron of TRAPPC6A.
What each result means
C/CTwo copies of the version the research linked to Alzheimer's disease (onset between ages 58 and 79). That is the strongest link of the three results. A link in a study is not a diagnosis.
C/TOne copy of the version the research linked to Alzheimer's disease (onset between ages 58 and 79). That is a smaller link than two copies.
T/TNo copy of the version the research linked to Alzheimer's disease (onset between ages 58 and 79). This is the starting point the study compared everyone against.
rs192775394 is a single position in the genome, in or near the TRAPPC6A gene. Published research associates it with alzheimer's disease (onset between ages 58 and 79). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs192775394 linked to?
On MyGeneLog this position is linked to Alzheimer's Disease. The research behind each link, and its sources, are set out on that condition page.
Does having rs192775394 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs192775394 come from?
GWAS Catalog, Neurobiology of aging 2019, PMID:30979435. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 312Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon0Apple0China (ByteDance, Huawei, Baidu…)0Others2Total3Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Alzheimer's disease (onset between ages 58 and 79) (rs192775394). MyGeneLog™. https://www.mygenelog.com/variants/rs192775394