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Triglyceride levels x long total sleep time interaction (1df test)

INTU · rs192018195

Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.

What the study found

Who was studied 48,568 African ancestry individuals, 7,410 East Asian ancestry individuals, 617,823 European ancestry individuals, 29,583 Hispanic/Latino individuals, 7,619 South Asian ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.0781 lower (95% confidence interval 0.052-0.104); p = 5 × 10⁻⁹.

How common The C allele had a frequency of about 99% in the people studied.

Where it sits Chromosome 4, band 4q28.1 — in an intron of INTU.

What each result means

C/C Two copies of the version the research linked to Triglyceride levels x long total sleep time interaction (1df test). That is the strongest link of the three results. A link in a study is not a diagnosis.

C/G One copy of the version the research linked to Triglyceride levels x long total sleep time interaction (1df test). That is a smaller link than two copies.

G/G No copy of the version the research linked to Triglyceride levels x long total sleep time interaction (1df test). This is the starting point the study compared everyone against.

Source

Genome-wide gene-sleep interaction study identifies novel lipid loci in 732,564 participants

Noordam R, Wang W, Nagarajan P, Wang H, Brown MR, Bentley AR, Hui Q, Kraja AT, Morrison JL, O'Connel JR, Lee S, Schwander K

and 137 more — show all

Bartz TM, de Las Fuentes L, Feitosa MF, Guo X, Hanfei X, Harris SE, Huang Z, Kals M, Lefevre C, Mangino M, Milaneschi Y, van der Most PJ, Pacheco NL, Palmer ND, Rao V, Rauramaa R, Sun Q, Tabara Y, Vojinovic D, Wang Y, Weiss S, Yang Q, Zhao W, Zhu W, Ansari MAY, Aschard H, Anugu P, Assimes TL, Attia J, Baker LD, Ballantyne C, Bazzano L, Boerwinkle E, Cade B, Chen HH, Chen W, Ida Chen YD, Chen Z, Cho K, De Anda-Duran I, Dimitrov L, Do A, Edwards T, Faquih T, Hingorani A, Fisher-Hoch SP, Gaziano JM, Gharib SA, Giri A, Ghanbari M, Grabe HJ, Graff M, Charles Gu C, He J, Heikkinen S, Hixson J, Ho YL, Hood MM, Houghton SC, Karvonen-Gutierrez CA, Kawaguchi T, Kilpeläinen TO, Komulainen P, Lin HJ, Linchangco GV Jr, Luik AI, Ma J, Meigs JB, McCormick JB, Menni C, Nolte IM, Norris JM, Petty LE, Polikowsky HG, Raffield LM, Rich SS, Riha RL, Russ TC, Ruiz-Narvaez EA, Sitlani CM, Smith JA, Snieder H, Sofer T, Shen B, Tang J, Taylor KD, Teder-Laving M, Triatin R, Tsai MY, Völzke H, Westerman KE, Xia R, Yao J, Young KL, Zhang R, Zonderman AB, Zhu X, Below JE, Cox SR, Evans M, Fornage M, Fox ER, Franceschini N, Harlow SD, Holliday E, Ikram MA, Kelly T, Lakka TA, Lawlor DA, Li C, Liu CT, Mägi R, Manning AK, Matsuda F, Morrison AC, Nauck M, North KE, Penninx BW, Province MA, Psaty BM, Rotter JI, Spector TD, Wagenknecht LE, van Dijk KW, Jaquish CE, Wilson PW, Peyser PA, Munroe PB, de Vries PS, Gauderman WJ, Sun YV, Chen H, Miller CL, Winkler TW, Rao DC, Redline S, van Heemst D

Lifelines Cohort Study · Million Veteran Program

Atherosclerosis · 2026 · PMID 41325697

Questions about rs192018195

What is rs192018195?

rs192018195 is a single position in the genome, in or near the INTU gene. Published research associates it with triglyceride levels x long total sleep time interaction (1df test). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs192018195 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs192018195 come from?

GWAS Catalog, Atherosclerosis 2026, PMID:41325697. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Triglyceride levels x long total sleep time interaction (1df test) (rs192018195). MyGeneLog™. https://www.mygenelog.com/variants/rs192018195

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