Sensitive

Venous thromboembolism

LRP4 · rs191945075

Where this position leads

Condition: Venous Thromboembolism

rs191945075 Condition: Venous Thromboembolism Venous Thromboembolism Condition rs191945075 rs191945075 LRP4

What the study found

Who was studied 29,435 European ancestry cases, 799 African American cases, 157,769 European ancestry controls, 14,353 African American controls.

The effect Each copy of the A allele carried 1.86 times the odds of Venous thromboembolism (95% confidence interval 1.68-2.07); p = 1 × 10−31.

Where it sits Chromosome 11, band 11p11.2 — in an intron of LRP4.

What each result means

A/A Two copies of the version the research linked to Venous thromboembolism. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Venous thromboembolism. That is a smaller link than two copies.
G/G No copy of the version the research linked to Venous thromboembolism. This is the starting point the study compared everyone against.
Source

Questions about rs191945075

What is rs191945075?

rs191945075 is a single position in the genome, in or near the LRP4 gene. Published research associates it with venous thromboembolism. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs191945075 linked to?

On MyGeneLog this position is linked to Venous Thromboembolism. The research behind each link, and its sources, are set out on that condition page.

Does having rs191945075 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs191945075 come from?

GWAS Catalog, Blood 2019, PMID:31420334. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Venous thromboembolism (rs191945075). MyGeneLog™. https://www.mygenelog.com/variants/rs191945075

← See all variants