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TFPI protein levels

CALCRL-AS1 · rs1918898

What the study found

Who was studied 496 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.441 higher (95% confidence interval 0.33-0.55); p = 8 × 10−15.

Where it sits Chromosome 2, band 2q32.1 — in an intron of CALCRL-AS1.

What each result means

C/C No copy of the version the research linked to TFPI protein levels. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to TFPI protein levels. That is a smaller link than two copies.
T/T Two copies of the version the research linked to TFPI protein levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs1918898

What is rs1918898?

rs1918898 is a single position in the genome, in or near the CALCRL-AS1 gene. Published research associates it with tfpi protein levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs1918898 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs1918898 come from?

GWAS Catalog, Scientific reports 2024, PMID:38565889. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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TFPI protein levels (rs1918898). MyGeneLog™. https://www.mygenelog.com/variants/rs1918898

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