Sensitive

Metabolic syndrome

SIK3 · rs191655881

Where this position leads

Condition: Metabolic Syndrome

rs191655881 Condition: Metabolic Syndrome Metabolic Syndrome Condition rs191655881 rs191655881 SIK3

What the study found

Who was studied 24,171 Taiwanese ancestry cases, 83,059 Taiwanese ancestry controls.

The effect Each copy of the A allele shifted the measure 0.0971 lower (95% confidence interval 0.066-0.128); p = 5 × 10−10.

How common The A allele had a frequency of about 13% in the people studied.

Where it sits Chromosome 11, band 11q23.3 — in an intron of SIK3.

What each result means

A/A Two copies of the version the research linked to Metabolic syndrome. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/C One copy of the version the research linked to Metabolic syndrome. That is a smaller link than two copies.
C/C No copy of the version the research linked to Metabolic syndrome. This is the starting point the study compared everyone against.
Source

Questions about rs191655881

What is rs191655881?

rs191655881 is a single position in the genome, in or near the SIK3 gene. Published research associates it with metabolic syndrome. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs191655881 linked to?

On MyGeneLog this position is linked to Metabolic Syndrome. The research behind each link, and its sources, are set out on that condition page.

Does having rs191655881 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs191655881 come from?

GWAS Catalog, Nutrients 2023, PMID:38201907. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Metabolic syndrome (rs191655881). MyGeneLog™. https://www.mygenelog.com/variants/rs191655881

← See all variants