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Who was studied 394,642 European ancestry individuals.
The effect
Each copy of the G allele shifted the measure 0.0502 higher (95% confidence interval 0.046-0.054); p = 1 × 10−127.
How common The G allele had a frequency of about 69% in the people studied.
Where it sits Chromosome 4, band 4q31.21 — inside GUSBP5.
What each result means
A/ANo copy of the version the research linked to Reticulocyte percentage (UKB data field 30240). This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Reticulocyte percentage (UKB data field 30240). That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Reticulocyte percentage (UKB data field 30240). That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature genetics · 2025 · PMID 39789286 · open access
Questions about rs1912742
What is rs1912742?
rs1912742 is a single position in the genome, in or near the GUSBP5 gene. Published research associates it with reticulocyte percentage (ukb data field 30240). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs1912742 linked to?
On MyGeneLog this position is linked to Celiac Disease. The research behind each link, and its sources, are set out on that condition page.
Does having rs1912742 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs1912742 come from?
GWAS Catalog, Nature genetics 2025, PMID:39789286. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Reticulocyte percentage (UKB data field 30240) (rs1912742). MyGeneLog™. https://www.mygenelog.com/variants/rs1912742