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Who was studied 56 Greater Middle Eastern ancestry cases, 5 unknown ancestry cases, 36 Greater Middle Eastern ancestry controls.
The effect
The reported allele is A; the catalogue records no effect size
; p = 2 × 10−11.
How common The A allele had a frequency of about 35% in the people studied.
Where it sits Chromosome 3, band 3q22.3 — a missense change in ESYT3.
What each result means
A/ATwo copies of the version the research linked to Hodgkin's lymphoma. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Hodgkin's lymphoma. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Hodgkin's lymphoma. This is the starting point the study compared everyone against.
International journal of laboratory hematology · 2021 · PMID 34216518
Questions about rs191240658
What is rs191240658?
rs191240658 is a single position in the genome, in or near the ESYT3 gene. Published research associates it with hodgkin's lymphoma. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs191240658 linked to?
On MyGeneLog this position is linked to Hodgkin Lymphoma. The research behind each link, and its sources, are set out on that condition page.
Does having rs191240658 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs191240658 come from?
GWAS Catalog, International journal of laboratory hematology 2021, PMID:34216518. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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