Sensitive

Colorectal cancer

PLXNA4 · rs190984989

Where this position leads

Condition: Colorectal Cancer

rs190984989 Condition: Colorectal Cancer Colorectal Cancer Condition rs190984989 rs190984989 PLXNA4

What the study found

Who was studied 4,988 European ancestry cases, 310,272 European ancestry controls.

The effect Each copy of the C allele shifted the measure 0.917 higher (95% confidence interval 0.61-1.22); p = 3 × 10−9.

Where it sits Chromosome 7, band 7q32.3 — in an intron of PLXNA4.

What each result means

C/C Two copies of the version the research linked to Colorectal cancer. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Colorectal cancer. That is a smaller link than two copies.
T/T No copy of the version the research linked to Colorectal cancer. This is the starting point the study compared everyone against.
Source

Questions about rs190984989

What is rs190984989?

rs190984989 is a single position in the genome, in or near the PLXNA4 gene. Published research associates it with colorectal cancer. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs190984989 linked to?

On MyGeneLog this position is linked to Colorectal Cancer. The research behind each link, and its sources, are set out on that condition page.

Does having rs190984989 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs190984989 come from?

GWAS Catalog, Scientific reports 2024, PMID:38538606. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Colorectal cancer (rs190984989). MyGeneLog™. https://www.mygenelog.com/variants/rs190984989

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