Who was studied 2,733 European ancestry cases, 346,689 European ancestry controls, 411 East Asian ancestry cases, 178,071 East Asian ancestry controls.
The effect
Each copy of the T allele shifted the measure 2.77 higher (95% confidence interval 1.83-3.71); p = 7 × 10−9.
Where it sits Chromosome 7, band 7p14.2 — between genes, 70.8 kb from TBX20.
What each result means
C/CPublished research associates this genotype with typical/baseline likelihood of Dysentery — no copies of the reported risk allele.
C/TPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Dysentery.
T/TPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Dysentery compared to the general population.
rs190894416 is a single position in the genome, in or near the near TBX20 gene. Published research associates it with dysentery. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs190894416 linked to?
On MyGeneLog this position is linked to Colon Polyp. The research behind each link, and its sources, are set out on that condition page.
Does having rs190894416 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs190894416 come from?
GWAS Catalog, Nature genetics 2021, PMID:34594039. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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