Sensitive

Celiac disease (PheCode 557.1)

LINC01016 · rs190732321

Where this position leads

Condition: Celiac Disease

rs190732321 Condition: Celiac Disease Celiac Disease Condition rs190732321 rs190732321 LINC01016

What the study found

Who was studied 1,036 European ancestry cases, 455,312 European ancestry controls.

The effect Each copy of the T allele shifted the measure 2.15 higher (95% confidence interval 1.46-2.84); p = 1 × 10−9.

How common The T allele had a frequency of about 1% in the people studied.

Where it sits Chromosome 6, band 6p21.31 — inside LINC01016.

What each result means

C/C No copy of the version the research linked to Celiac disease (PheCode 557.1). This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Celiac disease (PheCode 557.1). That is a smaller link than two copies.
T/T Two copies of the version the research linked to Celiac disease (PheCode 557.1). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs190732321

What is rs190732321?

rs190732321 is a single position in the genome, in or near the LINC01016 gene. Published research associates it with celiac disease (phecode 557.1). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs190732321 linked to?

On MyGeneLog this position is linked to Celiac Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs190732321 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs190732321 come from?

GWAS Catalog, Nature genetics 2021, PMID:34737426. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Celiac disease (PheCode 557.1) (rs190732321). MyGeneLog™. https://www.mygenelog.com/variants/rs190732321

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