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CTSC protein levels

near Y_RNA · rs190603325

Where this position leads

Condition: Celiac Disease

rs190603325 Condition: Celiac Disease Celiac Disease Condition rs190603325 rs190603325 near Y_RNA

What the study found

Who was studied 47,745 European ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.527 higher (95% confidence interval 0.37-0.69); p = 8 × 10−12.

How common The G allele had a frequency of about 0% in the people studied.

Where it sits Chromosome 11, band 11q14.2 — between genes, 9 kb from Y_RNA.

What each result means

C/C No copy of the version the research linked to CTSC protein levels. This is the starting point the study compared everyone against.
C/G One copy of the version the research linked to CTSC protein levels. That is a smaller link than two copies.
G/G Two copies of the version the research linked to CTSC protein levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs190603325

What is rs190603325?

rs190603325 is a single position in the genome, in or near the near Y_RNA gene. Published research associates it with ctsc protein levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs190603325 linked to?

On MyGeneLog this position is linked to Celiac Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs190603325 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs190603325 come from?

GWAS Catalog, Nature genetics 2025, PMID:39789286. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

CTSC protein levels (rs190603325). MyGeneLog™. https://www.mygenelog.com/variants/rs190603325

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