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Polyunsaturated fatty acids to monounsaturated fatty acids ratio

PAFAH1B2 · rs190584084

What the study found

Who was studied 239,268 European ancestry individuals.

The effect The reported allele is T; the catalogue records no effect size ; p = 1 × 10−10.

Where it sits Chromosome 11, band 11q23.3 — in an intron of PAFAH1B2.

What each result means

C/C No copy of the version the research linked to Polyunsaturated fatty acids to monounsaturated fatty acids ratio. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Polyunsaturated fatty acids to monounsaturated fatty acids ratio. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Polyunsaturated fatty acids to monounsaturated fatty acids ratio. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs190584084

What is rs190584084?

rs190584084 is a single position in the genome, in or near the PAFAH1B2 gene. Published research associates it with polyunsaturated fatty acids to monounsaturated fatty acids ratio. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs190584084 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs190584084 come from?

GWAS Catalog, HGG advances 2025, PMID:40545721. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Polyunsaturated fatty acids to monounsaturated fatty acids ratio (rs190584084). MyGeneLog™. https://www.mygenelog.com/variants/rs190584084

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