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Lipoprotein A levels (UKB data field 30790)

PLG · rs190381942

What the study found

Who was studied 394,642 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.935 higher (95% confidence interval 0.88-0.99); p = 7 × 10−226.

How common The T allele had a frequency of about 0% in the people studied.

Where it sits Chromosome 6, band 6q26 — in an intron of PLG.

What each result means

C/C Published research associates this genotype with typical/baseline likelihood of Lipoprotein A levels (UKB data field 30790) — no copies of the reported risk allele.
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Lipoprotein A levels (UKB data field 30790).
T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Lipoprotein A levels (UKB data field 30790) compared to the general population.
Source

Questions about rs190381942

What is rs190381942?

rs190381942 is a single position in the genome, in or near the PLG gene. Published research associates it with lipoprotein a levels (ukb data field 30790). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs190381942 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs190381942 come from?

GWAS Catalog, Nature genetics 2025, PMID:39789286. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Lipoprotein A levels (UKB data field 30790) (rs190381942). MyGeneLog™. https://www.mygenelog.com/variants/rs190381942

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