Standard

Medication use (glucocorticoids)

TSLP · rs1898671

Where this position leads

Condition: Medication Use as a Genetic Trait

rs1898671 Condition: Medication Use as a Genetic Trait Medication Use as a Genetic Trait Condition rs1898671 rs1898671 TSLP

What the study found

Who was studied 17,352 European ancestry cases, 188,348 European ancestry controls.

The effect Each copy of the T allele shifted the measure 0.0975 higher (95% confidence interval 0.075-0.12); p = 8 × 10−17.

How common The T allele had a frequency of about 35% in the people studied.

Where it sits Chromosome 5, band 5q22.1 — in an intron of TSLP.

What each result means

C/C Published research associates this genotype with typical/baseline likelihood of Medication use (glucocorticoids) — no copies of the reported risk allele.
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Medication use (glucocorticoids).
T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Medication use (glucocorticoids) compared to the general population.
Source

Questions about rs1898671

What is rs1898671?

rs1898671 is a single position in the genome, in or near the TSLP gene. Published research associates it with medication use (glucocorticoids). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs1898671 linked to?

On MyGeneLog this position is linked to Medication Use as a Genetic Trait. The research behind each link, and its sources, are set out on that condition page.

Does having rs1898671 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs1898671 come from?

GWAS Catalog, Nat Commun 2019, PMID:31015401. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Medication use (glucocorticoids) (rs1898671). MyGeneLog™. https://www.mygenelog.com/variants/rs1898671

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