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GLIPR1 protein levels

near LINC02500 · rs189525155

Where this position leads

Condition: Celiac Disease

rs189525155 Condition: Celiac Disease Celiac Disease Condition rs189525155 rs189525155 near LINC025…

What the study found

Who was studied 47,745 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.667 lower (95% confidence interval 0.48-0.85); p = 1 × 10−12.

How common The T allele had a frequency of about 0% in the people studied.

Where it sits Chromosome 4, band 4q34.3 — between genes, 88.8 kb from LINC02500.

What each result means

C/C Published research associates this genotype with typical/baseline likelihood of GLIPR1 protein levels — no copies of the reported risk allele.
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with GLIPR1 protein levels.
T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of GLIPR1 protein levels compared to the general population.
Source

Questions about rs189525155

What is rs189525155?

rs189525155 is a single position in the genome, in or near the near LINC02500 gene. Published research associates it with glipr1 protein levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs189525155 linked to?

On MyGeneLog this position is linked to Celiac Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs189525155 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs189525155 come from?

GWAS Catalog, Nature genetics 2025, PMID:39789286. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

GLIPR1 protein levels (rs189525155). MyGeneLog™. https://www.mygenelog.com/variants/rs189525155

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